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產(chǎn)品規(guī)格
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BN41748R-50ul
50ul
￥1486.00
交叉反應(yīng)：Human,Mouse(predicted:Rat,Dog,Pig,Cow) 推薦應(yīng)用：WB,ELISA
BN41748R-100ul
100ul
￥2360.00
交叉反應(yīng)：Human,Mouse(predicted:Rat,Dog,Pig,Cow) 推薦應(yīng)用：WB,ELISA
BN41748R-200ul
200ul
￥3490.00
交叉反應(yīng)：Human,Mouse(predicted:Rat,Dog,Pig,Cow) 推薦應(yīng)用：WB,ELISA
產(chǎn)品描述
| 英文名稱(chēng) | EAAT3 |
| 中文名稱(chēng) | 膠質(zhì)細(xì)胞谷氨酸運(yùn)載蛋白3/神經(jīng)/上皮細(xì)胞谷氨酸運(yùn)載蛋白抗體 |
| 別 名 | Excitatory amino acid transporters 3; Slc1a1; Eaac1; Eaat3; SLC1A1; EAAC1; EAAT3; solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1; EAAC 2; Excitatory amino acid carrier 1; Excitatory amino acid carrier 2; Excitatory amino acid carrier1; MEAAC 1; MEAAC1; Neuronal and epithelial glutamate transporter; REAAC 1; REAAC1; Slc1 a1; Slc1a 1; Slc1a1; Sodium dependent glutamate/aspartate transporter 3; Solute carrier family 1, member 1; EAA3_HUMAN. |
| 研究領(lǐng)域 | 免疫學(xué) 神經(jīng)生物學(xué) |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應(yīng) | Human, Mouse, (predicted: Rat, Dog, Pig, Cow, ) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000 ELISA=1:5000-10000 Flow-Cyt=1ug/Test not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 58kDa |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human EAAT3:451-524/524 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 產(chǎn)品介紹 | This gene encodes a member of the high-affinity glutamate transporters that play an essential role in transporting glutamate across plasma membranes. In brain, these transporters are crucial in terminating the postsynaptic action of the neurotransmitter glutamate, and in maintaining extracellular glutamate concentrations below neurotoxic levels. This transporter also transports aspartate, and mutations in this gene are thought to cause dicarboxylicamino aciduria, also known as glutamate-aspartate transport defect. Function: Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium. Negatively regulated by ARL6IP5 (By similarity). Subunit: Interacts with ARL6IP5/PRAF3. Subcellular Location: Membrane; Multi-pass membrane protein. Tissue Specificity: Expressed in all tissues tested including liver, muscle, testis, ovary, retinoblastoma cell line, neurons and brain (in which there was dense expression in substantia nigra, red nucleus, hippocampus and in cerebral cortical layers). Post-translational modifications: Glycosylated. Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family. SLC1A1 subfamily. SWISS: P43005 Gene ID: 6505 Database links: Entrez Gene: 6505 Human Entrez Gene: 20510 Mouse Omim: 133550 Human SwissProt: P43005 Human SwissProt: P51906 Mouse Unigene: 444915 Human Unigene: 246670 Mouse Unigene: 6384 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 膠質(zhì)細(xì)胞谷氨酸運(yùn)載蛋白3又稱(chēng)：神經(jīng)/上皮細(xì)胞谷氨酸運(yùn)載蛋白 |
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